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Magna Carta - 15th June, 1215

 
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1973 - First Imports - UK Starts to Import Factor VIII Products
The UK starts to import Factor VIII products as early as 1973
Source: Berridge (1977), Garfield (1994)
Type: First Imports
Location: UK
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1976, 25 March - MHRA / Armour (Medicines and Healthcare Regulatory Agency)
The MHRA grants a product licence for Factor VIII (PL 00231/0038 FACTORATE INJECTION - HEAT) to Armour Pharmaceutical Company Limited.

Note: The granting of this licence is one of the earliest Factor VIII product licences that we know of.

The licence documentation for this product clearly states the word "HEAT" in the description of the licence name. The word is in brackets but it appears that some text is missing, as the brackets are not closed. It is interesting to note the use of the word HEAT as early as March 1976.

Source: Medicines and Healthcare Regulatory Agency (MHRA) Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
http://www.taintedblood.info/tlfiles/MHRA Licences 1974 to 1978.pdf
Type: MHRA Licence
Location: USA
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1976, 27 August - MHRA / Porton Speywood Ltd
The MHRA grants Porton Speywood Ltd a product licence for Factor VIII (PL 03070/0004 HUMANATE AHF CONCENTRATE).
Source: Medicines and Healthcare Regulatory Agency (MHRA) Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
http://www.taintedblood.info/tlfiles/MHRA Licences 1974 to 1978.pdf
Type: MHRA Licence
Location: UK
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1976, 15 October - MHRA / Baxter
The MHRA grants a product licence to Baxter Healthcare Limited for Factor IX (PL 00116/0049 PROPLEX FACTOR IX COMPLEX.
Source: Medicines and Healthcare Regulatory Agency (MHRA) Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
http://www.taintedblood.info/tlfiles/MHRA Licences.pdf
Type: MHRA Licence
Location: USA
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1977, 3 February - MHRA / Lister Institute of Preventative Medicine - Product Licence
The MHRA grants Lister Institute of Preventative Medicine a product licence for Factor VIII (PL 00134/0007 HUMAN ANTIHAEMOPHILIC FRACTION).
Source: Medicines and Healthcare Regulatory Agency (MHRA) Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
http://www.taintedblood.info/tlfiles/MHRA Licences.pdf
Type: MHRA Licence
Location: UK
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1977, 3 March - MHRA / Lister Institute of Preventative Medicine - Product Licence
The MHRA grants Lister Institute of Preventative Medicine a product licence for Dried Factor VIII Fraction (PL 00134/0008 OCTOCOG ALFA).
Source: Medicines and Healthcare Regulatory Agency (MHRA) Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
http://www.taintedblood.info/tlfiles/MHRA Licences.pdf
Type: MHRA Licence
Location: UK
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1978, 26 September - MHRA / Common Services Agency (CSA) - Product Licence
The MHRA grants a product licence to the Common Services Agency (CSA) for Factor VIII (PL 03473/0007 HUMAN ANTIHAEMOPHILIC FRACTION
Source: Medicines and Healthcare Regulatory Agency (MHRA) Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
http://www.taintedblood.info/tlfiles/MHRA Licences.pdf
Type: MHRA Licence
Location: UK
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1979, 13 June - MHRA / Armour Product Licence
The MHRA grants Armour Pharmaceuticals Co Ltd a product licence for Factor VIII (PL 00231/0044 HIGH POTENCY FACTORATE PFR).
Source: Medicines and Healthcare Regulatory Agency (MHRA) Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
http://www.taintedblood.info/tlfiles/MHRA Licences.pdf
Type: MHRA Licence
Location: USA
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1979, 16 July - MHRA / Common Services Agency (CSA)
The MHRA grants a product licence to the Common Services Agency (CSA) for Factor IX (PL 03473/0008 HUMAN FACTOR IX CONCENTRATE POWDER (HTDEFIX) FRACTION.
Source: Medicines and Healthcare Regulatory Agency (MHRA) Licence:
http://www.taintedblood.info/tlfiles/MHRA Licences.pdf
Type: MHRA Licence. Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
Location: Scotland
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1979, 10 September - MHRA / Alpha Product Licence
The MHRA grants a product licence to Alpha Therapeutic GMBH, Langen, Germany for Factor VIII (PL 04029/0001 PROFILATE INJECTION).
Source: Medicines and Healthcare Regulatory Agency (MHRA) Marketing Authorisation, Product Licences for Clotting Factors Granted 1974-1978.
http://www.taintedblood.info/tlfiles/MHRA Licences.pdf
Type: MHRA Licence
Location: Germany
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